The midfielder missed Saturday's 2-0 win over Notts County with a knock but will be given as much time as possible to prove his fitness.
If he recovers in time, Thompson will be the only change to an otherwise full-fit squad.
Tisdale is likely to continue with the 3-5-2 formation which was so successful against the Magpies, meaning John O'Flynn will continue to partner veteran striker Jamie Cureton in attack.
Daniel Nardiello will be amongst the substitutes again despite scoring four goals in his last five appearances.
The Grecians will be looking to secure back-to-back league wins for the first time since November.
Source: PA
Source: PA